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Science and Evidence

Research, position statements, CIRS evidence, and the scientific debates behind mold-related illness care.

9 articles

Latest in science and evidence

Use this collection to go deeper on one part of mold-related illness, from first questions to the practical decisions that follow.

EvidenceCIRS

Actinos and CIRS: how to know when mold is not the whole story

What each CIRS test can and cannot tell you about actinobacteria, and where MoldCo can help interpret outside results.

SMDr. Scott McMahon / May 28, 2026 / 10 min read
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EvidenceCIRS

CDC Mold Illness and CIRS: Why the Agency Has Never Evaluated the Evidence

The CDC hasn't rejected CIRS. It's never evaluated it. Its mold guidance still rests on a 2004 report written before 98% of the evidence existed.

SMDr. Scott McMahon / May 28, 2026 / 12 min read
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EvidenceCIRS

112 of 114 studies on water-damaged buildings: what the evidence shows

The Dooley-McMahon 2020 water-damaged buildings review found 112 of 114 epidemiological studies (98.2%) support a link to single- and multi-system illness.

SMDr. Scott McMahon / May 28, 2026 / 13 min read
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EvidenceCIRS

Triple positive CIRS: what the Shoemaker research shows, and what it doesn't

Triple positive CIRS is a transcriptomic subset described in Shoemaker-lineage publications. Learn what the papers report, what remains open, and why it is not routine.

SMDr. Scott McMahon / May 28, 2026 / 10 min read
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EvidenceCIRS

The ACOEM Mold Paper: $500/Hour Expert Witnesses and What the Science Actually Shows

The ACOEM 2002 mold paper was written by defense expert witnesses, flagged internally as advocacy, and pulled in 2015. Here's what the evidence actually says.

SMDr. Scott McMahon / May 18, 2026 / 9 min read
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EvidenceCIRS

ACMT 2025 mold position statement: what it covers, what it doesn't

The ACMT 2025 mold position statement addresses mycotoxicosis, not CIRS. We break down its 32 references, what they actually evaluate, and what they leave out.

SMDr. Scott McMahon / May 13, 2026 / 9 min read
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EvidenceCIRS

CIRS Survival Guide: When You Can't Afford to Move

Broke, sick, stuck in a moldy home? An honest guide to CIRS when you can't afford to move - what actually works, what to skip, and a $56 starting point.

SMDr. Scott McMahon / May 7, 2026 / 12 min read
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EvidenceCIRS

Why Nobody Else in Your Building Is Sick (and You Can't Get Out of Bed)

CIRS is a genetic inflammatory condition that explains why mold makes some people severely ill while others feel nothing. Learn the science behind the 24/76 split.

SMDr. Scott McMahon / April 27, 2026 / 7 min read
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EvidenceCIRS

Is CIRS a Real Diagnosis? What the Peer-Reviewed Evidence Shows

CIRS has more published evidence than ME/CFS, which the CDC already recognizes. Here's what the peer-reviewed literature actually says.

SMDr. Scott McMahon / April 15, 2026 / 13 min read
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